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Results Found: 8
  • Breast Invasive Carcinoma (TCGA, PanCancer Atlas) data

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 1,084 breast invasive carcinomas from 1,084 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    DNA Mutational Analysis
    Access Rights
    Free to All
  • TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK),...

    Subject
    DNA Mutational Analysis
    Immunotherapy
    Mutation
    Tumor Burden
    Access Rights
    Free to All
  • SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018): MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of HER2- and HER3-mutant tumors. The data was generated utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, Amplification Status, Best objective response rate, Bubble...

    Subject
    Breast Neoplasms
    Carcinoma, Hepatocellular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Colorectal Neoplasms
    DNA Mutational Analysis
    Endometrial Neoplasms
    Esophageal Neoplasms
    Genes, erbB
    Genes, erbB-2
    Melanoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Salivary Gland Neoplasms
    Sarcoma
    Skin Neoplasms
    Urinary Bladder Neoplasms
    Uterine Cervical Neoplasms
    Access Rights
    Free to All
  • Tumors with TRK fusions (MSK, 2019): Tumors with TRK fusions based on MSK-IMPACT targeted sequencing.

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of tropomyosin receptor kinase (TRK) fusion tumors. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), information about mutated genes, patient demographics, and modality. The data set also...

    Subject
    DNA Mutational Analysis
    Oncogene Proteins, Fusion
    Receptor Protein-Tyrosine Kinases
    Receptor, trkA
    Receptor, trkB
    Receptor, trkC
    Access Rights
    Free to All
  • Breast Invasive Carcinoma (TCGA, Firehose Legacy)

    Description

    TCGA Breast Invasive Carcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 1,108 carcinomas from 1,101 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...

    Subject
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    DNA Mutational Analysis
    Skin Neoplasms
    Access Rights
    Free to All
  • Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal

    Description

    This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Neuroendocrine
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Cell-Free Nucleic Acids
    Choriocarcinoma
    Endodermal Sinus Tumor
    Melanoma
    Neoplasms, Germ Cell and Embryonal
    Neoplasms, Squamous Cell
    Neuroendocrine Tumors
    Prostatic Neoplasms
    Seminoma
    Small Cell Lung Carcinoma
    Urinary Bladder Neoplasms
    Access Rights
    Free to All
  • Breast Cancer (MSK, Cancer Cell 2018): Targeted Sequencing of tumor/normal sample pairs from 1918 Breast cancers.

    Description

    This dataset contains the summary data visualizations and clinical data from targeted sequencing of tumor/normal sample pairs from 1,918 Breast cancers from 1,756 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sample Type, Sex, Disease Free (Months), Disease Free Event, ER PCT Primary, ER Status of Sequenced Sample, ER Status...

    Subject
    Breast Carcinoma In Situ
    Breast Neoplasms
    Carcinoma, Adenoid Cystic
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    Access Rights
    Free to All
  • Data from: Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions

    Authors
    Andrade, Victor P.
    Ostrovnaya, Irina
    Seshan, Venkatraman
    Morrogh, Mary
    6 more author(s)...
    Description

    Summary from Dryad: "Abstract: INTRODUCTION: Lobular carcinoma in situ (LCIS) has been accepted as a marker of risk for the development of invasive breast cancer, yet modern models of breast carcinogenesis include LCIS as a precursor of low-grade carcinomas. We provide evidence favoring a clonal origin for LCIS and synchronous estrogen receptor-positive malignant lesions of the ductal and lobular...

    Subject
    Biomarkers, Tumor
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    Access Rights
    Free to All